英文名：Hyaluronidase (Ronidase)
中文名：玻璃酸酯，玻璃糖醛酸酶，玻璃样酸酶，透明质酸酶
说明：透明质酸酶(hyaluronidase,HAase)是能使透明质酸产生低分子化作用酶的总称,一种能够降低体内透明质酸的活性，从而提高组织中液体渗透能力的酶。
用途：为一种能水解透明质酸的酶(透明质酸为组织基质中具有限制水分及其它细胞外物质扩散作用的成分)，用于人体能暂时降低细胞间质的粘性，可促使皮下输液、局部积贮的渗出液或血液加快扩散而利于吸收，为一种重要的药物扩散剂。临床用作药物渗透剂，促进药物的吸收，促进手术及创伤后局部水肿或血肿消散。
Simga相关产品资料
Sigma H3506 Hyaluronidase from bovine testes
Type I-S, lyophilized powder, 400-1000 units/mg solid
Synonym: Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase
CAS Number: 37326-33-3
Enzyme Commission (EC) Number: 3.2.1.35 ( BRENDA | IUBMB )
EC Number: 253-464-3
MDL number: MFCD00131351
Description
Frequently Asked Questions Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions These enzymes randomly cleave β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.
Other Notes View more information on enzymes for complex carbohydrate analysis at Unit Definition One unit will cause a change in A600 of 0.330 per minute at pH 5.7 at 37°C in a 2.0 ml reaction mixture (45 minute assay).
Properties
type Type I-S
form lyophilized powder
mol wt mol wt ~55 kDa (four subunits of 14 kDa each)
storage temp. −20°C
Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements 22-24/25
WGK Germany 3